Increasing evidence suggests that the carriers of intercellular communication are extracellular vesicles (EVs). They are a heterogeneous population of membrane particles released into the extracellular space in vitro and in vivo, or example exosomes and microvesicles. But how these structures are signaling from one cell to another remains elusive. We study systematically the secretion and signaling of EVs in the context of cell migration in tumor cells and in vivo in Drosophila melanogaster. We focus on the cell biological mechanisms of EVs release.
How do cells communicate?
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Extracellular Signaling Lab
Health and Medical University
Ernst von Bergmann Clinic